2017. Thompson A et al. – New insights into the burden and costs of multiple sclerosis in Europe: Results for the United Kingdom

 

Thompson A, Kobelt G, Berg J, Capsa D, Eriksson J, Miller D; European Multiple Sclerosis Platform. New insights into the burden and costs of multiple sclerosis in Europe: Results for the United Kingdom. Mult Scler. 2017 Aug;23(2_suppl):204-16.

https://www.ncbi.nlm.nih.gov/pubmed/28643587

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Abstract

INTRODUCTION: In order to estimate the value of interventions in multiple sclerosis (MS) – where lifetime costs and outcomes cannot be observed – outcome data have to be combined with costs. This requires that cost data be regularly updated.

OBJECTIVES AND METHODS: This study is part of a cross-sectional retrospective study in 16 countries collecting data on resource consumption and work capacity, health-related quality of life (HRQoL) and prevalent symptoms for patients with MS. Descriptive analyses are presented by level of disability, from the societal perspective, in EUR (2015).

RESULTS: A total of 779 patients (mean age = 57 years) participated; 72% were below retirement age and of these, 36% were employed. Employment was related to disease severity, and MS affected productivity at work for 84% of patients. Overall, 96% and 72% of the patients experienced fatigue and cognition as a problem. Mean utility and annual costs were 0.735 and 11,400GBP at Expanded Disability Status Scale (EDSS) = 0-3, 0.534 and 22,700GBP at EDSS = 4-6.5, and 0.135 and 36,500GBP at EDSS = 7-9. The mean cost of a relapse was estimated at 790GBP.

CONCLUSION: This study illustrates the burden of MS on UK patients and provides current data on MS that are important for development of health policies.